The Value of Microbes in Cancer Neoantigen Immunotherapy

Tumor neoantigens are widely used in cancer immunotherapy, and a growing body of research suggests that microbes play an important role these neoantigen-based immunotherapeutic processes. The human its surrounding environment filled with large number long-term interaction the organism. microbiota can modulate our immune system, help activate neoantigen-reactive T cells, great process targeting tumor for therapy. Recent studies have revealed interconnection between neoantigens, which cross-react each other through molecular mimicry, providing theoretical guidance more relevant studies. current applications immunotherapy against mainly focused on vaccine development checkpoint inhibitors. This article summarizes related fields importance neoantigens.